Port St Lucie is a vibrant city located on the east coast of Florida, making it a popular destination for tourists and business travelers alike. When flying to this picturesque area, there are several nearby airports that provide convenient access. The closest airport to Port St Lucie is Palm Beach International Airport, situated approximately 50 miles south of the city. This well-connected airport offers a wide range of domestic and international flights as well as numerous ground transportation options for seamless travel to Port St Lucie. Another option is Fort Lauderdale-Hollywood International Airport, located approximately 86 miles to the south. Known for its efficiency and extensive flight connections, this airport serves as an alternative gateway for travelers heading to Port St Lucie.